Dr. Leah Chase-Wallar has been at Hope since 2000.

See Dr. Chase-Wallar's current research 

AREAS OF INTEREST

• Regulation of cystine/glutamate exchange by system x_c^-

EDUCATION

• Ph.D., University of Minnesota, 1999
• B.S., University of Michigan – Flint, 1993

GRANTS

• Campbell Foundation, “Studies of the Regulation of System x_c¯ Activity in a Dopamergic Cell,” 2005–2007
• Towsley Research Scholar Program, “Mechanistic and Regulatory Studies of a Neurotransmitter Transport System,” 2003–2006
• Campbell Foundation, “Regulation of a Neurotransmitter Transporter by Reactive Oxygen Species,” 2003–2005
• NSF, “Development of a project-oriented Neuroscience lab at Hope College,” 2002–2003
• NSF-CCLI, “Development of a project-oriented Neuroscience lab at Hope College,” 2002–2003
• Campbell Foundation, “Mechanistic and regulatory studies of a neurotransmitter transporter,” 2001–2003
• Campbell Foundation, “Mechanistic and regulatory studies of a neurotransmitter transport system,” 2001
• Hope College, Faculty Development Grant, 2001

Published Works

• “The Lathyrus Toxin, b-N-oxalyl-L-a,b-diaminoproprionic acid (ODAP) and Homocysteic Acid Sensitize CA1 Pyramidal Neurons to Cystine and L-Amino-6-Phosphonohexanoic Acid,” Toxicology and Applied Pharmacology, 219(1), 2007
• “l-Quisqualic Acid Transport into Hippocampal Neurons by a l-Cystine-Sensitive Carrier is Required for the Induction of l-Quisqualate Sensitization,” Journal of Neuroscience, 106(2), 2001
• “Abolition of Quisqualate Sensitization and Enhancement of Potency for Depolarization by Quisqualate in 24-hour Hippocampal Slices briefly exposed to Quisqualate,” Society for Neuroscience, Abst. 26, 2000
• “Differentiation of Two Na+-Independent Glutamate Transport Subtypes in Rat Hippocampal Slices,” Society for Neuroscience, Abst. 25, 1999
• “Effects of Quisqualic Acid Analogs on Metabotropic Glutamate Receptors Coupled to Phosphoinositide Hydrolysis in Rat Hippocampus,” Neuropharmacology, 34, 1995
• “Type 4a Metabotropic Glutamate Receptor: Identification of New Potent Agonists and Differentiation from the l-(+)2-Amino-4-Phosphonobutanoic Acid Sensitive Receptor in the Lateral Perforant Pathway in Rats,” Molecular Pharmacology, 48, 1995
• “Aspects of Nitrogen and Mineral Nutrition in Icelandic Reindeer, Rangifer tarandus,” Journal of Comparative Biochemistry and Physiology, 109A, 1994

Outside the College

When she’s not working at Hope, Leah enjoys spending time with her husband, Brad, and their children. In the summer, they enjoy camping, going to the beach and bike riding on Mackinac Island.